72 research outputs found

    Individualisation and student responses to higher education tuition fees in the UK, 1998-2003

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    To this day, the introduction of Higher Education tuition fees during the 1990s proves to be a contentious issue. Despite their financial implications few students actively oppose them. I conducted a detailed study on the issue of the £1000 tuition fees introduced in 1998. I aimed to explore why Higher Education students do not take part in campaigns opposing tuition fees. My research was guided by drawing upon the individualisation theory developed by Beck (1992, 2002) and Giddens (1991). The empirical element of the research is based on a sample of students taken from two universities in the same city. It is argued that many Higher Education students do not actively participate in campaigns against tuition fees because they perceive their education to be an investment and accept that debt is a fact of life. It is further argued that students see themselves as individualised consumers who, as a result pursue individual rather than collective solutions to resolving problems related to educational provision. Though the students who participated in this research overwhelmingly believed the state should pay university tuition fees few students actively oppose them. This research argues that they have a low sense of political efficacy and perceive themselves to be a socially marginalised group with little significance in the eyes of politicians and society. Findings of this research enable the lack of active opposition towards tuition fees to be understood in its social context. Beck and Giddens’ analytical framework provides a practical explanation of why many students do not take part in these campaigns. However, it needs to be developed to provide a more coherent explanation of why so few students actively oppose tuition fees

    Individualisation and student responses to higher education tuition fees in the UK, 1998-2003

    Get PDF
    To this day, the introduction of Higher Education tuition fees during the 1990s proves to be a contentious issue. Despite their financial implications few students actively oppose them. I conducted a detailed study on the issue of the £1000 tuition fees introduced in 1998. I aimed to explore why Higher Education students do not take part in campaigns opposing tuition fees. My research was guided by drawing upon the individualisation theory developed by Beck (1992, 2002) and Giddens (1991). The empirical element of the research is based on a sample of students taken from two universities in the same city. It is argued that many Higher Education students do not actively participate in campaigns against tuition fees because they perceive their education to be an investment and accept that debt is a fact of life. It is further argued that students see themselves as individualised consumers who, as a result pursue individual rather than collective solutions to resolving problems related to educational provision. Though the students who participated in this research overwhelmingly believed the state should pay university tuition fees few students actively oppose them. This research argues that they have a low sense of political efficacy and perceive themselves to be a socially marginalised group with little significance in the eyes of politicians and society. Findings of this research enable the lack of active opposition towards tuition fees to be understood in its social context. Beck and Giddens’ analytical framework provides a practical explanation of why many students do not take part in these campaigns. However, it needs to be developed to provide a more coherent explanation of why so few students actively oppose tuition fees.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

    Clinical and laboratory characterization of patients with localized scleroderma and response to UVA-1 phototherapy: In vivo and in vitro skin models

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    Background/Purpose Localized scleroderma (LS) is a rare disease leading to progressive hardening and induration of the skin and subcutaneous tissues. LS is responsive to UVA-1 phototherapy, though its exact mechanism of action dermal fibrosis is yet to be fully elucidated. We aimed to investigate the molecular changes induced by UVA-1 rays in human primary fibroblasts cultures. Methods A total of 16 LS patients were treated with medium-dose UVA-1 phototherapy. At baseline, during and after therapy, Localized Scleroderma Assessment Tool, Dermatology Life Quality Index and lesions' staging and mapping were performed along with high-frequency ultrasound (HFUS) examination for dermal thickness assessment. Gene expression analysis for 23 mRNA transcripts, in vitro UVA-1 irradiation and viability tests were realized on lesional fibroblasts' primary cultures, before and 3 months after therapy. Results The dermal thickness, the LoSCAT and the DLQI progressively decreased starting from the last phototherapy session up to the 6 and 9 month follow-ups (-57% and -60%, respectively). Molecular gene analysis (rt-PCR) revealed that UVA-1 phototherapy exerts multiple effects: the activation of specific anti-fibrotic pathways (e.g., overexpression of CTHRC1 and metalloproteases 1, 2, 7, 8, 9, 12, suppression of TIMP-1), the downregulation of peculiar pro-fibrotic pathways (e.g., downregulation of TGF-ss, TGF-ssrII, Grb2, SMAD 2/3, TNRSF12A, CTGF) through a significant overexpression of IL-1ss; the stabilization of collagen synthesis acting on genes COL1A1, COL3A1, COL8A1, COL10A1, COL12A1. Conclusion UVA-1 phototherapy adds significant benefits in local tissue remodeling, rebalancing the alteration between pro-fibrotic and anti-fibrotic pathways; these changes can be well monitored by HFUS. © 2022 The Authors
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